DHT: Powerful Sex Hormone

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Dihydrotestosterone, commonly known as DHT, is a sex steroid and androgen hormone. The most famous androgen hormone is testosterone, but DHT has equal importance in male development. People assume that testosterone is the only male sex hormone. I will show you that DHT is just as important as testosterone.

Everything in the body (skin, genitalia, central nervous system, etc.), except muscle, interacts with its active androgen, called DHT.

Testosterone is just a guide that converts to DHT through the enzyme 5alpha reductase (5‑AR). Because 5‑AR is located in practically every cell of the body except muscle cells, little or no testosterone binds to those androgen receptors. You get the point: Where 5‑AR is, the DHT does the work, not testosterone.

If you take away 5‑AR, you would see changes in physiognomy. A rare disorder called pseudohermaphroditism is a condition that occurs when you have a 5‑AR deficiency. Since DHT plays a significant role in the development of secondary sex characteristics, infants with this disorder have underdeveloped male genitalia and prostates, which results in their being raised as girls. When puberty knocks, their testosterone levels elevate normally, but DHT stays very low. They are muscular like other boys, but they lack body hair and have underdeveloped prostates and penises.

The Glory of DHT

DHT protects you against estrogen, the primary female sex hormone. If you took 5‑AR inhibitor, you could end up developing gynecomastia, also known as “man-tits.” By reducing protection (DHT) against estrogen, you are causing feminization of your male body.

Experts say DHT is 3 to 10 times stronger than testosterone. The brain relies on sex hormones like testosterone, DHEA, DHT, and estrogen for its functioning, but all of them are secondary to DHT when speaking of brain health and well-being. The neural effect of DHT on the brain lasts 24 hours, while that of testosterone lasts only a few hours.

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